Rituximab and Castleman disease and Kaposi's sarcoma
نویسندگان
چکیده
منابع مشابه
Rituximab therapy for HIV-associated Castleman disease.
To assess the clinical benefit of rituximab for HIV-associated Castleman disease, 5 patients infected with HIV with histologic-proven Castleman disease were prospectively enrolled to receive 4 infusions of rituximab. Clinical and biologic parameters (C-reactive protein, CD19 cell count, Kaposi sarcoma-associated herpesvirus [KSHV] viral load in peripheral blood mononuclear cells) were assessed ...
متن کاملSimultaneous lymph node involvement by Castleman disease and Kaposi sarcoma
Both multicentric Castleman disease and Kaposi sarcoma are more frequently observed in HIV infected patients. The coexistence of these Human herpesvirus 8 related lesions, in the same tissue, has been observed, but literature reports are scant. On the other hand, the expression of HHV-8-LANA-1 is easily demonstrable by immunohistochemistry. This has been shown to be a powerful tool for the diag...
متن کاملKaposis sarcoma in a Nairobi hospital.
BACKGROUND Kaposi's sarcoma (KS) is associated epidemiologically with HIV infection and a number of countries have reported a dramatic increase in the incidence of KS with the advent of AIDS. Although AIDS is prevalent in Kenya, no studies on the impact of AIDS on the pattern of KS has been carried out. OBJECTIVE To determine any changes in the pattern of KS that might have occurred since the...
متن کاملEpidemiology, Pathophysiology, and Treatment of Kaposi Sarcoma–Associated Herpesvirus Disease: Kaposi Sarcoma, Primary Effusion Lymphoma, and Multicentric Castleman Disease
Ryan J. Sullivan, Liron Pantanowitz, Corey Casper, Justin Stebbing, and Bruce J. Dezube Division of Hematology and Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, and Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts; Departments of Medicine and Epidemiology, University of Washington, and Vaccine and...
متن کاملHuman and viral interleukin-6 and other cytokines in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.
Kaposi sarcoma herpesvirus (KSHV)-associated multicentric Castleman disease (MCD) is a polyclonal B-cell lymphoproliferative disorder. Human (h) IL-6 and a KSHV-encoded homolog, viral IL-6, have been hypothesized to contribute to its pathogenesis, but their relative contributions to disease activity is not well understood. We prospectively characterized KSHV viral load (VL), viral (v) and hIL-6...
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ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2008
ISSN: 1758-2652
DOI: 10.1186/1758-2652-11-s1-p290